PF-06291826(Tafamidis)|cas 594839-88-0

PF-06291826(Tafamidis)|cas 594839-88-0

DC Chemicals, Website:www.dcchemicals.com

Product Name: PF-06291826(Tafamidis)|CAS: 594839-88-0|Cat No: DC10756|Other Names: Tafamidis,cas 594839-88-0,PF-06291826,PF06291826

Tafamidis is a novel specific transthyretin (TTR) stabilizer or dissociation inhibitor.

Tafamidis is a novel specific transthyretin (TTR) stabilizer or dissociation inhibitor. TTR is a tetramer that is responsible in transporting the retinol-binding protein-vitamin A complex and minimally transporting thyroxine in the blood. In TTR-related disorders such as transthyretin familial amyloid polyneuropathy (TTR-FAP), tetramer dissociation is accelerated that results in unregulated amyloidogenesis and amyloid fibril formation. Eventually the failure of autonomic and peripheral nervous system is induced.