GLPG-1837(ABBV-974)|GLPG1837|cas 1654725-02-6

GLPG-1837(ABBV-974)|GLPG1837|cas 1654725-02-6

DC Chemicals, Website:www.dcchemicals.com

Product Name: GLPG-1837(ABBV-974)|CAS: 1654725-02-6|Cat No: DC10753|Other Names: GLPG-1837; GLPG 1837; GLPG1837; ABBV-974; ABBV 974; ABBV974,1654725-02-6

GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator.

GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. GLPG1837 was generally safe and well tolerated in healthy subjects up to the highest dose of 800 mg twice daily for 2 weeks. GLPG1837 shows enhanced efficacy on CFTR mutants harboring Class III mutations compared to Ivacaftor, the first marketed potentiator.