ML 221|ML221|CAS 877636-42-5

ML 221|ML221|CAS 877636-42-5

DC Chemicals, Website:www.dcchemicals.com

Product Name: ML221|CAS: 877636-42-5|Cat No: DC10793|Other Names: ML221; ML 221; ML-221

ML221 is an antagonist of the apelin (APJ) receptor.

Apelin receptor (APJ) antagonist (IC50 values are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively). Displays >37-fold selectivity over the closely related angiotensin II type 1 (AT1) receptor. Exhibits no toxicity towards human hepatocytes at concentrations >50 μM.