2018年5月18日星期五

M-3814(nedisertib)|CAS 1637542-33-6

M-3814(nedisertib)|CAS 1637542-33-6

DC Chemicals, Website:www.dcchemicals.com

Product Name: M-3814(nedisertib)|CAS: 1637542-33-6|Cat No: DC10749|Other Names: MSC2490484A; MSC-2490484A; MSC 2490484A; M3814; M-3814; M 3814; nedisertib

M-3814(nedisertib) is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities.

M-3814(nedisertib) is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities. Upon oral administration, the DNA-PK inhibitor MSC2490484A binds to and inhibits the activity of DNA-PK. This inhibits the ability of tumor cells to repair damaged DNA, which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK.


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