M2698|MSC-2363318A|cas 1379545-95-5
DC Chemicals, Website:www.dcchemicals.com
Product Name: M2698(MSC-2363318A)|CAS: 1379545-95-5|Cat No: DC10751|Other Names: M2698; M-2698; M 2698; MSC-2363318A; MSC 2363318A; MSC2363318A
M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier.
M2698, also known as MSC-2363318A, is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. M2698 was highly potent in vitro (IC50 1 nM for p70S6K, Akt1 and Akt3 inhibition; IC50 17 nM for pGSK3β indirect inhibition) and in vivo (IC50 15 nM for pS6 indirect inhibition), and relatively selective (only 6/264 kinases had an IC50 within 10-fold of p70S6K).
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