Ciliobrevin A(HPI4)|ciliogenesis/Hedgehog pathway inhibitor-4

Ciliobrevin A(HPI4)|ciliogenesis/Hedgehog pathway inhibitor-4

Ciliobrevin A(HPI-4) is a Hedgehog pathway inhibitor and ciliogenesis inhibitor.

Product Name: Ciliobrevin A(HPI4)|Cat No: DC9875|cas: 302803-72-1|Other Names: HPI-4,HPI 4

HPI-4 is a Hedgehog pathway inhibitor and ciliogenesis inhibitor. The Hedgehog (HH) signaling pathway is targeted for anti-cancer therapeutics and HPI-4 blocks Sonic hedgehog (Shh)-induced hedgehog pathway activation (IC50 = 7 μM) downstream of Smo. It also inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

For the research and scientific use only, not for human use!