AM-2099|AM2099|NaV1.7 Inhibitor

AM-2099|AM2099|NaV1.7 Inhibitor

AM-2099 is a potent and selective NaV1.7 Inhibitor.

Product Name: AM2099|Cat No: DC9909|cas: 1443373-17-8 |Other Names: AM 2099,AM-2099

AM-2099 is a potent and selective NaV1.7 Inhibitor (hNav1.7 IC50 = 0.16 uM; hNav1.5 IC50 > 30 uM; Papp = 31 x 10 (-6)cm/s; Rat IV CL (b/h/kg) \= 0.54; cLogD = 2.1). AM-2099 demonstrated a favorable pharmacokinetic profile in rat and dog and demonstrated dose-dependent reduction of histamine-induced scratching bouts in a mouse behavioral model following oral dosing.

For the research and scientific use only, not for human use!