IDE-2|IDE2|ESCs inducer

IDE-2|IDE2|ESCs inducer

IDE-2 is a cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs).

Product Name: IDE-2|Cat No: DC9971|cas: 1136466-93-7|Other Names: IDE-2,IDE 2,IDE2

IDE-2 is a cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs). Reported to activate TGF-β signaling and downstream Smad2 phosphorylation; upregulates Nodal expression. Promotes pancreatic progenitor cell formation in vitro, and gut tube formation in vivo.

For the research and scientific use only, not for human use!