Lanabecestat|AZD3293|LY-3314814|BACE1 inhibitor
AZD3293 is a potent and selective orally active, brain-permeable BACE1 inhibitor,currently in development as a potential treatment for early Alzheimer’s disease.
Product Name: Lanabecestat(AZD3293,LY-3314814)|Cat No: DC9946|cas: 1383982-64-6|Other Names: AZD 3293,LY3314814,AZD-3293,LY 3314814
AZD3293 is an, orally administered, inhibitor of BACE1, the β-secretase sheddase that cleaves the APP protein to release APP's C99 fragment. This fragment then becomes a substrate for subsequent γ-secretase cleavage and Aβ peptide generation. The rationale is that inhibiting BACE1 will reduce amyloid-related toxicity in Alzheimer's disease. AZD3293 is one of several BACE1/2 inhibitors currently in development.
For the research and scientific use only, not for human use!
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