MK-4827(Niraparib,MK4827)|PARP inhibitor

MK-4827(Niraparib,MK4827)|PARP inhibitor

MK-4827 is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity.

Product Name: Niraparib(MK4827) hydrochloride|Cat No: DC9862|cas: 1038915-64-8|Other Names: MK 4827,MK-4827,MK4827

Description of MK-4827: MK-4827 is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway. The specific PARP family member target  For PARP inhibitor MK4827 is unknown. Check  For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
 For the detailed information about the solubility of MK-4827  in water, the solubility of MK-4827  in DMSO, the solubility of MK-4827  in PBS buffer, the animal experiment（test） of MK-4827, the in vivo,in vitro and clinical trial test of MK-4827, the cell experiment（test） of MK-4827, the IC50, EC50 and Affinity of MK-4827 , please contact DC Chemicals.

For the research and scientific use only, not for human use!