CPI-1205|CPI1205|EZH2 inhibitor

CPI-1205|CPI1205|EZH2 inhibitor

CPI-1205 is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.

Product Name: CPI-1205|Cat No: DC9908|cas: 1621862-70-1 |Other Names: CPI 1205,CPI1205

CPI-1205 is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2. Upon oral administration, CPI-1205 selectively inhibits the activity of both wild-type and mutated forms of EZH2. Inhibition of EZH2 specifically prevents the methylation of histone H3 on lysine 27 (H3K27). This decrease in histone methylation alters gene expression patterns associated with cancer pathways and results in decreased proliferation of EZH2-expressing cancer cells.

For the research and scientific use only, not for human use!