2016年12月29日星期四

Lusutrombopag|S-888711|TPO receptor agonist

Lusutrombopag|S-888711|TPO receptor agonist

Lusutrombopag(S-888711) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

Product Name: Lusutrombopag(S-888711)|Cat No: DC9938|cas: 1110766-97-6 |Other Names: S888711,S 888711

Lusutrombopag, also known as S-888711, is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels. In September 2015, lusutrombopag received its first global approval in Japan for the improvement of CLD-associated thrombocytopenia in patients scheduled to undergo elective invasive procedures.

For the research and scientific use only, not for human use!

没有评论:

发表评论