2016年12月28日星期三

GW0742|GW-0742|PPARδ agonistDC Chemicals

GW0742|GW-0742|PPARδ agonistDC Chemicals

GW-0742 is a potent and highly selective PPARδ agonist.

Product Name: GW0742|Cat No: DC9904|cas: 317318-84-6|Other Names: GW 0742,GW-0742

GW-0742 is a potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.

For the research and scientific use only, not for human use!

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