BMT145027，BMT-145027|mGluR5 PAM

BMT145027，BMT-145027|mGluR5 PAM

BMT-145027 is a potent mGluR5 PAM with no inherent mGluR5 agonist activity.

Product Name: BMT-145027|Cat No: DC9937|cas: N/A|Other Names: BMT145027，BMT 145027

BMT-145027 is a potent mGluR5 PAM with no inherent mGluR5 agonist activity. BMT-145027 is a non-MPEP site PAM to demonstrate in vivo efficacy. BMT-145027 has mGluR5 PAM EC50 = 47 nM, with fold shit = 3.5, and is effective in mouse NOR. The metabotropic glutamate receptor 5 (mGluR5) is an attractive target for the treatment of schizophrenia due to its role in regulating glutamatergic signaling in association with the N-methyl-D-aspartate receptor (NMDAR).

For the research and scientific use only, not for human use!