UNC3866|UNC-3866|CBX4/CBX7 chromodomains antagonist

UNC3866|UNC-3866|CBX4/CBX7 chromodomains antagonist

UNC3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains.

Product Name: UNC3866|Cat No: DC9965|cas: 1872382-47-2|Other Names: UNC 3866,UNC-3866

UNC3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains. UNC3866 was also highly selective versus >250 other molecular targets including chromatin regulatory proteins and a general pharmacology panel. UNC3866 was enabled in part by the use of molecular dynamics simulations performed with CBX7 and its endogenous substrate.

For the research and scientific use only, not for human use!