Selonsertib|GS-4997|GS4997|ASK1 inhibitor

Selonsertib|GS-4997|GS4997|ASK1 inhibitor

Selonsertib（GS-4997）is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

Product Name: Selonsertib（GS-4997）|Cat No: DC9873|cas: 1448428-04-3|Other Names: GS4997，GS 4997

Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.

For the research and scientific use only, not for human use!