SSD114|SSD-114|GABAB positive allosteric modulator
DC Chemicals, Website:www.dcchemicals.com
Product Name: SSD-114|CAS: N/A|Cat No: DC10651|Other Names: SSD114,SSD 114,SSD-114
SSD114 is a novel GABAB positive allosteric modulator.
SSD114 is a novel GABAB positive allosteric modulator. SSD114 potentiates the GABA inhibition of adenylyl-cyclase mediated by GABAB receptors. SSD114 is also effective in vivo potentiating baclofen-induced sedation/hypnosis in mice, with no effect when tested alone. These findings indicate that SSD114, a molecule with a different chemical structure compared to known GABAB PAMs, is a novel GABAB PAM with potential usefulness in the GABAB-receptor research field.
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