Curaxin|CBL0137|CAS 1197996-80-7|FACT inhibitor

Curaxin|CBL0137|CAS 1197996-80-7|FACT inhibitor

DC Chemicals, Website:www.dcchemicals.com

Product Name: CBL0137|CAS: 1197996-80-7|Cat No: DC10617|Other Names: CBL0137; CBL-0137; CBL 0137; Curaxin

CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM.

CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. CBL0137 has broad anticancer activity in mice when administered orally, eradicates drug-resistant cancer stem cells, and potentiates efficacy of gemcitabine (Item No. 11690) in preclinical models of pancreatic cancer.