BMS-986158|bromodomain/extra-terminal (BET)inhibitor|cas 1800340-40-2

BMS-986158|bromodomain/extra-terminal (BET)inhibitor|cas 1800340-40-2


DC Chemicals, Website:www.dcchemicals.com

Product Name: BMS-986158|CAS: 1800340-40-2|Cat No: DC10609|Other Names: BMS-986158,BMS 986158,BMS986158

BMS-986158 is an inhibitor of the bromodomain and extra-terminal (BET) proteins.

BMS-986158 is an inhibitor of the bromodomain and extra-terminal (BET) proteins. BMS-986158 is an inhibitor of the bromodomain (BRD) and extra-terminal domain (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.