STF-31|STF31|GLUT1 inhibitor|DC Chemicals

STF-31|STF31|GLUT1 inhibitor|DC Chemicals

STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.

Product Name: STF-31 |Catalog Number: DC8359 |CAS 724741-75-7 |Other names: STF31,STF 31 |Chemical Name: 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide |Molecule Formular: C23H25N3O3S |MW: 423.5

STF-31 is an inhibitor of GLUT1 (IC50 = ~1 µM) that blocks glucose uptake.It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress GLUT1.Although STF-31 binds GLUT1, suggesting a direct effect, STF-31 also inhibits nicotinamide phosphoribosyltransferase, an enzyme that induces GLUT1 expression. STF-31 is also toxic to human pluripotent stem cells (hPSCs) and can be used to selectively eliminate hPSCs from mixed cultures. For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of  STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, For the detailed information of STF-31, the solubility of STF-31 in water, the solubility of STF-31 in DMSO, the solubility of STF-31 in PBS buffer, the animal experiment (test) of  STF-31, the cell expriment (test) of STF-31, the in vivo, in vitro and clinical trial test of STF-31, the EC50, IC50,and affinity,of STF-31, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.