Thiamet G is a potent and selective inhibitor of O-GlcNAcase that demonstrates a Ki value of 21 nM.
Product Name: Thiamet G |Catalog Number: DC8759 |CAS 1009816-48-1 |Other names: Thiamet-G |Chemical Name: |Molecule Formular: C9H16N2O4S |MW: 248.3
Thiamet G is a potent and selective inhibitor of O-GlcNAcase that demonstrates a Ki value of 21 nM.Thiamet G increases cellular O-GlcNAc-modified protein levels (EC50 = 30 nM) and blocks phosphorylation of tau protein both in cultured PC-12 cells and in rats (200 mg/kg/day). Thiamet G is the first highly potent O-GlcNAcase inhibitor known to be orally bioavailable and effectively cross the blood brain barrier.
For research only, not for human use!
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