2016年1月27日星期三

NQDI-1|ASK1 inhibitor| DC Chemicals

NQDI-1|ASK1 inhibitor| DC Chemicals

NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases.

Product Name: NQDI-1 |Catalog Number: DC8787 |CAS 175026-96-7 |Other names: NQDI-1,NQDI 1,NQDI1 |Chemical Name: 2,​7-​dihydro-​2,​7-​dioxo-3H-​naphtho[1,​2,​3-​de]​quinoline-​1-​carboxylic acid​, ethyl ester |Molecule Formular: C19H13NO4 |MW: 319.3

NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia.

For research only, not for human use!

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