PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.
Product Name: PF-04880594 |Catalog Number: DC8727 |CAS 1111636-35-1 |Other names: PF 04880594，PF04880594 |Chemical Name: 3-[[4-[1-(2,2-difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazol-4-yl]pyrimidin-2-yl]amino]propanenitrile |Molecule Formular: C19H16F2N8 |MW: 394.38
PF-04880594 is a potent and selective RAF inhibitor that inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 potently inhibits tumor growth in BRAF-mutant melanoma xenograft models.
For research and scientific purpose only, not for human use!
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