2016年1月7日星期四

SKQ1|cas 934826-68-3|DC Chemicals

SKQ1|cas 934826-68-3|DC Chemicals

SKQ1 prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices.

Product Name: SKQ1 |Catalog Number: DC8500 |CAS 934826-68-3 |Other names: SKQ1; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide; 10-(6-plastoquinolyl) decyltriphenylphosphonium bromide; Brand name: Visomitin |Chemical Name: (10-(4,5-dimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl)triphenylphosphonium bromide |Molecule Formular: C36H42BrO2P |MW: 617.6

SKQ1, also known as plastoquinonyl decyltriphenyl phosphonium or PDTP, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. SKQ1 showed activities to prevent amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices; (2) to reverse aging-related biomarkers in rats; (3) to slow down the development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats; (4) to increase the lifespan of male rodents under LP or SPF conditions. SKQ1 can penetrate cell membranes, and is proposed as an anti-aging treatment. Visomitin, which API is SKQ1, is currently under clinical trials for treating glaucoma in Russia

For research and scientific purpose only, not for human use.

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