GNE-490|cas 1033739-92-2|DC Chemicals

GNE-490|cas 1033739-92-2|DC Chemicals

GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR.

Product Name: GNE-490 |Catalog Number: DC8502 |CAS 1033739-92-2 |Other names: GNE490;GNE 490 |Chemical Name: 2-[6-(2-amino-4-methylpyrimidin-5-yl)-1-morpholin-4-yl-2,4-dihydrothieno[3,2-d]pyrimidin-3-yl]propan-2-ol |Molecule Formular: C18H22N6O2S |MW: 386.5

GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR. It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo. This compound represents an excellent tool to further evaluate the therapeutic potential of a PI3K inhibitor in the treatment of cancer.

For research and scientific purpose only, not for human use.