2016年1月4日星期一

SB-742457(RVT-101)|5-HT6 receptor inhibitor|DC Chemicals

SB-742457(RVT-101)|5-HT6 receptor inhibitor|DC Chemicals

SB-742457, also known as RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.

Product Name: SB-742457(RVT-101) |Catalog Number: DC8354 |CAS 607742-69-8 |Other names: SB 742457,RVT 101,SB742457,RVT101 |Chemical Name: 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline |Molecule Formular: C19H19N3O2S |MW: 353.12

SB-742457, also known as RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD. For the detailed information of SB-742457(RVT-101), the solubility of SB-742457(RVT-101) in water, the solubility of SB-742457(RVT-101) in DMSO, the solubility of SB-742457(RVT-101) in PBS buffer, the animal experiment (test) of  SB-742457(RVT-101), the cell expriment (test) of SB-742457(RVT-101), the in vivo, in vitro and clinical trial test of SB-742457(RVT-101), the EC50, IC50,and affinity,of SB-742457(RVT-101), For the detailed information of SB-742457(RVT-101), the solubility of SB-742457(RVT-101) in water, the solubility of SB-742457(RVT-101) in DMSO, the solubility of SB-742457(RVT-101) in PBS buffer, the animal experiment (test) of  SB-742457(RVT-101), the cell expriment (test) of SB-742457(RVT-101), the in vivo, in vitro and clinical trial test of SB-742457(RVT-101), the EC50, IC50,and affinity,of SB-742457(RVT-101), Please contact DC Chemicals.

For research and scientific purpose only, not for human use.

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