2016年1月7日星期四

KN-93(KN93)|CaMKII inhibitor|DC Chemicals

KN-93(KN93)|CaMKII inhibitor|DC Chemicals

Potent, cell permeable inhibitor of CaM kinase II (IC50 = 0.37 μM).

Product Name: KN-93(free base) |Catalog Number: DC8484 |CAS 139298-40-1 |Other names: KN-93,KN93,KN 93 |Chemical Name: N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide |Molecule Formular: C26H29ClN2O4S |MW: 501.04

Potent, cell permeable inhibitor of CaM kinase II (IC50 = 0.37 μM). Also a direct extracellular open channel blocker of voltage-gated potassium channels (IC50 = 307 nM for KV1.5); independent of CaM kinase II inhibition.

For research and scientific purpose only, not for human use.

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