Disodium (R)-2-Hydroxyglutarate|cas 103404-90-6|DC Chemicals

Disodium (R)-2-Hydroxyglutarate|cas 103404-90-6|DC Chemicals

Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.

Product Name: Disodium (R)-2-Hydroxyglutarate |Catalog Number: DC8385 |CAS 103404-90-6 |Other names:  |Chemical Name: sodium (R)-2-hydroxypentanedioate |Molecule Formular: C5H6Na2O5 |MW: 192.08

In U-87MG cells, (R)-2-Hydroxyglutarate acts as weak antagonists of α-KG to inhibit α-KG-dependent histone demethylases and increases dimethylation on both H3K9 and H3K79. [1] Besides, (R)-2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling, and thus causes growth arrest and tumor cell killing. [2] For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of  Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, For the detailed information of Disodium (R)-2-Hydroxyglutarate, the solubility of Disodium (R)-2-Hydroxyglutarate in water, the solubility of Disodium (R)-2-Hydroxyglutarate in DMSO, the solubility of Disodium (R)-2-Hydroxyglutarate in PBS buffer, the animal experiment (test) of  Disodium (R)-2-Hydroxyglutarate, the cell expriment (test) of Disodium (R)-2-Hydroxyglutarate, the in vivo, in vitro and clinical trial test of Disodium (R)-2-Hydroxyglutarate, the EC50, IC50,and affinity,of Disodium (R)-2-Hydroxyglutarate, Please contact DC Chemicals.

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