RS 102895 Hydrochloride is a CKR-2B (CCR2)-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CKR-2B and CKR-1 (CCR2b and CCR1 receptors) respectively).
Product Name: RS 102895 (hydrochloride) |Catalog Number: DC8587 |CAS 1173022-16-6 |Other names: |Chemical Name: 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |Molecule Formular: C21H21F3N2O2.HCl |MW: 426.86
RS 102895 Hydrochloride is a CKR-2B (CCR2)-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CKR-2B and CKR-1 (CCR2b and CCR1 receptors) respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Inhibits α1A-AR, α1D-AR and SR-1A (α1A, α1D and 5-HT1A receptors).
For research and scientific purpose only, not for human use.
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