PRE-084(PRE084)|Sigma-1 inhibitor|DC Chemicals

PRE-084(PRE084)|Sigma-1 inhibitor|DC Chemicals

PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively).

Product Name: PRE-084 hydrochloride |Catalog Number: DC8347 |CAS 75136-54-8 |Other names: PRE-084,PRE 084,PRE084 |Chemical Name: 2-(4-Morpholinethyl) 1-phenylcyclohexanecarboxylate hydrochloride |Molecule Formular: C19H27NO3.HCl |MW: 353.89

High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling. For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of  PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of  PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.