PF4618433|cas 1166393-85-6|DC Chemicals

PF4618433|cas 1166393-85-6|DC Chemicals

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796

Product Name: PF4618433 |Catalog Number: DC8526 |CAS 1166393-85-6 |Other names: PF4618433 |Chemical Name:  |Molecule Formular: C24H27N7O2 |MW: 445.5

Potent and selective PYK2 inhibitor. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization.

For research and scientific purpose only, not for human use.