MPEP-HCl| mGlu5a receptor inhibitor|DC Chemicals

MPEP-HCl| mGlu5a receptor inhibitor|DC Chemicals

MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM.

Product Name: MPEP hydrochloride |Catalog Number: DC8339 |CAS 219911-35-0 |Other names:  |Chemical Name: 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |Molecule Formular: C14H11N.HCl |MW: 229.71

Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.  For the detailed information of MPEP hydrochloride, the solubility of MPEP hydrochloride in water, the solubility of MPEP hydrochloride in DMSO, the solubility of MPEP hydrochloride in PBS buffer, the animal experiment (test) of  MPEP hydrochloride, the cell expriment (test) of MPEP hydrochloride, the in vivo, in vitro and clinical trial test of MPEP hydrochloride, the EC50, IC50,and affinity,of MPEP hydrochloride, For the detailed information of MPEP hydrochloride, the solubility of MPEP hydrochloride in water, the solubility of MPEP hydrochloride in DMSO, the solubility of MPEP hydrochloride in PBS buffer, the animal experiment (test) of  MPEP hydrochloride, the cell expriment (test) of MPEP hydrochloride, the in vivo, in vitro and clinical trial test of MPEP hydrochloride, the EC50, IC50,and affinity,of MPEP hydrochloride, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.