JNJ-38158471|cas 951151-97-6|DC Chemicals

JNJ-38158471|cas 951151-97-6|DC Chemicals

Product Name: JNJ-38158471 |Catalog Number: DC8521 |CAS 951151-97-6 |Other names: JNJ38158471 |Chemical Name:  |Molecule Formular: C15H17ClN6O3 |MW: 364.8

JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC(50) of 40nM. It also inhibits closely related tyrosine kinases such as Ret (IC(50) of 180nM) and Kit (C50 of 500nM). It has no significant activity (>1µM) against VEGFR-1 and VEGFR-3.

For research and scientific purpose only, not for human use.