3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay
Product Name: 3-(4-Pyridyl) |Catalog Number: DC8567 |CAS 7272-84-6 |Other names: Rho Kinase Inhibitor III; ROCK Inhibitor III; Rockout |Chemical Name: 3-(4-Pyridyl)indole |Molecule Formular: C13H10N2 |MW: 194.23
3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay.It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.
For research and scientific purpose only, not for human use.
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