Trospium chloride|cas 10405-02-4|DC Chemicals

Trospium chloride|cas 10405-02-4|DC Chemicals

Trospium Chloride is a competitive muscarinic cholinergic receptor antagonist.

Product Name: Trospium chloride|Cat No. DC9136|cas: 10405-02-4|Other names: | Molecule formular: C25H30ClNO3Molecule Weight: 427.96

Trospium Chloride is a competitive muscarinic cholinergic receptor antagonist.Trospium chloride is an antimuscarinic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Trospium has pharmacologic properties that are distinct from other antimuscarinic agents. After oral administration, absorption of the hydrophilic trospium chloride is slow and incomplete. Peak plasma concentrations (Cmax) of approximately 4 ng/mL are reached 4-5 hours after administration of a 20 mg immediate-release preparation. The mean bioavailability is approximately 10% and decreases by concomitant food intake (to a mean of 26% of the fasting area under the plasma concentration-time curve [AUC]). Trospium chloride displays dose proportional increases in AUC and Cmax after a single dose within the clinically relevant dose range (20-60 mg). The mean volume of distribution is approximately 350-800 L.

For research only, not for human use!