DL-AP7|CAS 78966-69-5|DC Chemicals

DL-AP7|CAS 78966-69-5|DC Chemicals

DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA.

Product Name: DL-AP7|Cat No. DC9250|cas: 78966-69-5|Other names: | Molecule formular: C7H16NO5PMolecule Weight: 225.2

DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA. Studies indicate that the S1 and S2 domains of the NMDA receptor are essential in DL-AP7 and other related antagonists to bind to the receptor. In addition, the positively charged Lys residues at the second interaction site and Arg at the fourth site are key factors in ligand binding. The NMDA receptor is unique in that it requires binding of two ligands, glutamate and glycine to become activated. As a result of its inhibitory affects, DL-AP7 is an ideal tool in studying signaling pathways and ion flow through the NMDA receptor.