2016年5月23日星期一

Mirin |cas 1198097-97-0|DC Chemicals

Mirin |cas 1198097-97-0|DC Chemicals

Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11.

Product Name: Mirin|Cat No. DC9275|cas: 1198097-97-0|Other names: Mirin| Molecule formular: C10H8N2O2SMolecule Weight: 220.25

Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50 = 12 μM) and induces G2 cell cycle arrest. Also blocks homology-directed repair in vitro.


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