2016年5月23日星期一

AZD9496|cas 1639042-08-2|DC Chemicals

AZD9496|cas 1639042-08-2|DC Chemicals

AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator(Ki=0.7 nM) and antagonist.

Product Name: AZD9496|Cat No. DC9268|cas: 1639042-08-2|Other names: AZD-9496,AZD 9496| Molecule formular: C25H25F3N2O2Molecule Weight: 442.47

AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator(Ki=0.7 nM) and antagonist.
AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.


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