RS-102895 hydrochloride|CAS 1173022-16-6|DC Chemicals

RS-102895 hydrochloride|CAS 1173022-16-6|DC Chemicals

RS 102895 hydrochloride is a chemokine receptor CCR2 antagonist.

Product Name: RS-102895 hydrochloride|Cat No. DC9251|cas: 1173022-16-6|Other names: RS-102895，RS 102895，RS102895| Molecule formular: C21H21F3N2O2.HClMolecule Weight: 426.86

RS 102895 Hydrochloride is a CKR-2B (CCR2)-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CKR-2B and CKR-1 (CCR2b and CCR1 receptors) respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Inhibits α1A-AR, α1D-AR and SR-1A (α1A, α1D and 5-HT1A receptors).