2016年5月22日星期日

Eliglustat|CAS 491833-29-5|Genz-99067

Eliglustat|CAS 491833-29-5|Genz-99067

Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.

Product Name: Eliglustat(Genz-99067)|Cat No. DC9290|cas: 491833-29-5|Other names: Genz-99067; Genz99067; Genz 99067| Molecule formular: C23H36N2O4Molecule Weight: 404.54

Eliglustat is a new promising substrate reduction therapy (SRT). [1] Eliglustat works by inhibiting UDP-glucosylceramide synthase, the first enzyme that catalyzes the biosynthesis of glycosphingolipids, thus reducing the load of glucosylceramide influx into the lysosome.
Eliglustat tartrate is a potent ceramide analog and has a selective inhibitory action on GLC synthase.


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