2016年10月8日星期六

S-2765,S2765 (Fxa Chromogenic substrate)

S-2765,S2765 (Fxa Chromogenic substrate)

S-2765 is specific to activated factor X (FXa),short peptide covalently bound to pNA (4-nitroaniline).

Product Name: S-2765(FXa substrate)|Cat No. DC9806|CAS: 113711-77-6|Other names:S2765 ,S 2765 |MW: 714.6|Molecule Formular: Z-D-Arg-Gly-Arg-pNA·2HCl|Purity>98%

S-2765, which is specific to activated factor X (FXa), is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by FXa, it releases a free pNA which could be detected by a spectrophotometer at 405 nm.S-2765 is mainly used in anti-FXa activity assay of heparin. S-2765 can be used in many applications, such as:
1:Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs.
2: Anti-factor Xa activities of heparin and LMWHs.
3: Activities of antithrombin and coagulation factors.
4: Anti-factor Xa activities of heparin and LMWHs in human plasma.
5: Production of kits for automated blood analyzers.
6: Evaluation of potential anticoagulants from chemical synthesis, bacterial fermentation and animal tissues.

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