2016年10月8日星期六

APS-3-77|KSR/RAS signaling modulator

APS-3-77|KSR/RAS signaling modulator

APS-3-77 is a novel modulator of KSR-dependent MAPK signalling,KSR2,IC50>10 uM

Product Name: APS-3-77|Cat No. DC9809|CAS: N/A|Other names:APS 3 77,APS377,APS-377|MW: 401.17|Molecule Formular: C24H23N3O3|Purity>98%

APS-3-77 is a novel modulator of KSR-dependent MAPK signalling,KSR2,IC50>10 Um,antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK (mitogen-activated protein kinase)


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