CFI-402257|CFI402257|TTK inhibitor

CFI-402257|CFI402257|TTK inhibitor

CFI-402257 is a highly potent and selective TTK (threonine tyrosine kinase) Inhibitor ((TTK Ki = 0.1 nM) with potential anticancer activity.

Product Name: CFI402257|Cat No. DC9740|CAS: 1610759-22-2|Other names:CFI402257,CFI 402257,CFI-402257 |MW: 497.2|Molecule Formular: C29H31N5O3|Purity>98%

CFI-402257 is a highly potent and selective TTK (threonine tyrosine kinase) Inhibitor ((TTK Ki = 0.1 nM) with potential anticancer activity. TTK is an essential chromosomal regulator and is overexpressed in aneuploid tumors. High TTK levels correlate with a high tumor grade11 and poor patient outcomes. TTK inhibition are associated with a disabled mitotic checkpoint, resulting in chromosome segregation errors, aneuploidy, and cell death.

For research only, not for human use.