2016年10月8日星期六

Dihexa (PNB-0408)

Dihexa (PNB-0408)

Dihexa is an oligopeptide drug that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met.

Product Name: Dihexa (PNB-0408)|Cat No. DC9760|CAS: 1401708-83-5|Other names:|MW: 504.67|Molecule Formular: C27H44N4O5|Purity>98%

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment.[1][2][3][4][5][6][7][8][9][10] In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

For research only, not for human use.

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