Mad2 inhibitor-1 (M2I-1)|cas 312271-03-7

Mad2 inhibitor-1 (M2I-1)|cas 312271-03-7

Mad2 Inhibitor-1 (M2I-1) is a small molecule protein-protein interaction inhibitor targeting the mitotic spindle assembly checkpoint.

Product Name: Mad2 inhibitor-1 (M2I-1)|Cat No. DC9741|CAS: 312271-03-7|Other names:M2I1,M2I 1,M2I-1|MW: 404.48|Molecule Formular: C19H24N4O4S|Purity>98%

Mad2 inhibitor-1 (M2I-1) is the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the SAC. M2I-1 disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. Cellular studies revealed that M2I-1 weakens the SAC response, indicating that the compound might be active in cells.

For research only, not for human use.