2016年10月8日星期六

IMR-1|IMR1|CAS 310456-65-6

IMR-1|IMR1|CAS 310456-65-6

IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.

Product Name: IMR-1|Cat No. DC9756|CAS: 310456-65-6|Other names:eFT 508,eFT-508|MW: 353.04|Molecule Formular: C15H15NO5S2|Purity>98%

IMR-1 disruptS the recruitment of Mastermind-like 1 to the Notch transcriptional activation complex on chromatin, thereby attenuating Notch target gene transcription. Furthermore, IMR-1 inhibited the growth of Notch-dependent cell lines and significantly abrogated the growth of patient-derived tumor xenografts.

For research only, not for human use.

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