CNDAC|active component of sapacitabine

CNDAC|active component of sapacitabine

CNDAC is the active component of sapacitabine.

Product Name: CNDAC|Cat No. DC9799|CAS: 135598-68-4|Other names:|MW: 250.11|Molecule Formular: C11H14N4O3|Purity>98%

CNDAC is the active component of sapacitabine. Sapacitabine is an oral nucleoside analog prodrug that acts through a dual mechanism. The compound interferes with DNA synthesis by causing single-strand DNA breaks and induces arrest of the cell division cycle at G2 phase.Both sapacitabine and its major metabolite, CNDAC, have demonstrated potent anti-tumor activity in both blood and solid tumors in preclinical studies. In a liver metastatic mouse model, sapacitabine was shown to be superior to gemcitabine or 5-FU, two widely used nucleoside analogs, in delaying the onset and growth of liver metastasis.