AM-2394|AM2394|Glucokinase agonist (GKA)

AM-2394|AM2394|Glucokinase agonist (GKA)

AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.

Product Name: AM-2394|Cat No: DC9830|cas: 1442684-77-6|Other Names: AM2394,AM 2394

AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394 activates GK with an EC50 of 60 nM, increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes

For the research and scientific use only, not for human use!