CAY10585|LW6|CAS 934593-90-5|HIF-1 inhibitor

CAY10585|LW6|CAS 934593-90-5|HIF-1 inhibitor

DC Chemicals, Website: www.dcchemicals.com

Product Name: CAY10585|Cas Number: 934593-90-5| Catalog Number: DC10516|Other Nmaes: CAY 10585,CAY-10585,CAY10585,LW6

CAY10585 prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 µM, respectively.

CAY10585 prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 µM, respectively. It blocks HIF-1α accumulation in Hep3B cells in a concentration and time-dependent manner, with complete inhibition at a concentration of 30 µM within 12 hours. CAY10585 also significantly suppresses transcription of the HIF-1 target genes VEGF and erythropoietin at 10 µM.