2017年12月10日星期日

Mitapivat|PKM2 activator|cas 1260075-17-9

Mitapivat|PKM2 activator|cas 1260075-17-9

DC Chemicals, Website: www.dcchemicals.com

Product Name: Mitapivat|Cas Number: 1260075-17-9 | Catalog Number: DC10568|Other Nmaes: Mitapivat,PKM2 activator,cas 1260075-17-9

Mitapivat  is an activator of pyruvate kinase isoenzyme M2 (PKM2)

Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it is hypothesized that PKM2 is a potential target for cancer therapy. Modulation of PKM2 might also be effective in the treatment of obesity, diabetes, autoimmune conditions, and antiproliferation-dependent diseases.

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